Description

Description

5-Fluoro-2-methylpyridine (CAS No. 31181-53-0) is a high-purity fluorinated pyridine derivative with the molecular formula C₆H₆FN. This heterocyclic compound is widely utilized in pharmaceutical, agrochemical, and materials science research due to its unique reactivity as a building block for complex organic synthesis. The presence of both fluorine and methyl substituents on the pyridine ring enhances its utility in nucleophilic aromatic substitution and metal-catalyzed coupling reactions. Our product is rigorously tested to ensure ??98% purity (GC) and is supplied in sealed, light-resistant packaging under inert atmosphere to guarantee stability. Available in quantities from grams to multi-kilogram scale, it is ideal for medicinal chemistry, ligand design, and specialty chemical applications.

Key Specifications:
– CAS: 31181-53-0
– Molecular Weight: 111.12 g/mol
– Appearance: Colorless to pale yellow liquid
– Boiling Point: ~145-148??C
– Density: ~1.1 g/cm³
– Storage: 2-8??C under nitrogen

Application

5-Fluoro-2-methylpyridine serves as a versatile intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology. Its electron-deficient pyridine core facilitates the development of kinase inhibitors and PET radiotracer precursors. In agrochemical research, it functions as a key scaffold for novel pesticides and herbicides. The compound’s fluorine moiety also enables its use in material science for designing liquid crystals and conductive polymers.

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