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Atomfair Methyl 5-bromopyridine-2-carboxylate methyl 5-bromopicolinate C7H6BrNO2

Description Methyl 5-bromopyridine-2-carboxylate (CAS No. 29682-15-3) is a high-purity brominated pyridine derivative with the molecular formula C7H6BrNO2. This compound is a versatile building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its structure features a reactive bromine substituent at the 5-position and an ester group at the 2-position, enabling diverse functionalization via cross-coupling reactions, nucleophilic substitutions, or hydrolysis. Supplied as a white to off-white crystalline solid with ??95% purity (HPLC), it is ideal for precision applications. Packaged under inert gas to ensure stability, this reagent is compatible with anhydrous conditions and sensitive synthetic protocols. Store in a cool,…

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Description

Description

Methyl 5-bromopyridine-2-carboxylate (CAS No. 29682-15-3) is a high-purity brominated pyridine derivative with the molecular formula C7H6BrNO2. This compound is a versatile building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its structure features a reactive bromine substituent at the 5-position and an ester group at the 2-position, enabling diverse functionalization via cross-coupling reactions, nucleophilic substitutions, or hydrolysis. Supplied as a white to off-white crystalline solid with ??95% purity (HPLC), it is ideal for precision applications. Packaged under inert gas to ensure stability, this reagent is compatible with anhydrous conditions and sensitive synthetic protocols. Store in a cool, dry place away from light and moisture to maintain optimal performance.

  • CAS No: 29682-15-3
  • Molecular Formula: C7H6BrNO2
  • Molecular Weight: 216.03
  • Exact Mass: 214.95819
  • Monoisotopic Mass: 214.95819
  • IUPAC Name: methyl 5-bromopyridine-2-carboxylate
  • SMILES: COC(=O)C1=NC=C(C=C1)Br
  • Synonyms: Methyl 5-bromopyridine-2-carboxylate, 2-Pyridinecarboxylic acid, 5-bromo-, methyl ester, 681-695-3, 29682-15-3, methyl 5-bromopicolinate

Application

Methyl 5-bromopyridine-2-carboxylate serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and ligands for catalysis. It is widely used in Suzuki-Miyaura and Buchwald-Hartwig coupling reactions to construct complex heterocyclic scaffolds. Researchers also employ it in the development of kinase inhibitors and other bioactive molecules due to its modular reactivity. Its ester group allows further derivatization to carboxylic acids or amides, expanding its utility in medicinal chemistry.

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