Atomfair

Awaiting product image

Atomfair 5-Bromo-4-chloro-6-cyclopropylpyrimidine C7H6BrClN2

Description 5-Bromo-4-chloro-6-cyclopropylpyrimidine (CAS No. 27192-21-8) is a high-purity halogenated pyrimidine derivative with the molecular formula C7H6BrClN2. This compound is a valuable heterocyclic building block for pharmaceutical and agrochemical research, featuring a reactive bromo-chloro substitution pattern and a cyclopropyl moiety that enhances steric and electronic modulation. Ideal for cross-coupling reactions , nucleophilic substitutions , and metal-catalyzed transformations , it is supplied as a crystalline solid with ??95% purity (HPLC). Packaged under inert gas to ensure stability, it is suited for high-throughput screening and medicinal chemistry applications. Store at 2-8??C in a dry environment.

Category:
Brands:

Description

Description

5-Bromo-4-chloro-6-cyclopropylpyrimidine (CAS No. 27192-21-8) is a high-purity halogenated pyrimidine derivative with the molecular formula C7H6BrClN2. This compound is a valuable heterocyclic building block for pharmaceutical and agrochemical research, featuring a reactive bromo-chloro substitution pattern and a cyclopropyl moiety that enhances steric and electronic modulation. Ideal for cross-coupling reactions, nucleophilic substitutions, and metal-catalyzed transformations, it is supplied as a crystalline solid with ??95% purity (HPLC). Packaged under inert gas to ensure stability, it is suited for high-throughput screening and medicinal chemistry applications. Store at 2-8??C in a dry environment.

  • CAS No: 27192-21-8
  • Molecular Formula: C7H6BrClN2
  • Molecular Weight: 233.49
  • Exact Mass: 231.94029
  • Monoisotopic Mass: 231.94029
  • IUPAC Name: 5-bromo-4-chloro-6-cyclopropylpyrimidine
  • SMILES: C1CC1C2=C(C(=NC=N2)Cl)Br
  • Synonyms: 5-bromo-4-chloro-6-cyclopropylpyrimidine, 27192-21-8, 823-376-5, MFCD11047047, SCHEMBL16441737

Application

5-Bromo-4-chloro-6-cyclopropylpyrimidine serves as a versatile intermediate in the synthesis of kinase inhibitors and antiviral agents due to its reactive halogen sites. Its cyclopropyl group facilitates the development of conformationally constrained bioactive molecules. Researchers utilize it in Suzuki-Miyaura and Buchwald-Hartwig couplings to construct complex heterocycles. It is also employed in crop protection chemistry for designing novel pesticides.

If you are interested or have any questions, please contact us at support@atomfair.com