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Atomfair Methyl 6-bromopyridine-2-carboxylate C7H6BrNO2

Description Methyl 6-bromopyridine-2-carboxylate (CAS No. 26218-75-7) is a high-purity brominated pyridine derivative with the molecular formula C7H6BrNO2. This compound is a versatile building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its structure features a reactive bromine substituent at the 6-position and an ester group at the 2-position, enabling further functionalization via cross-coupling reactions, nucleophilic substitutions, or hydrolysis. Ideal for Suzuki, Stille, or Buchwald-Hartwig couplings, this reagent is supplied as a crystalline solid with ??95% purity (HPLC). Store under inert conditions at 2-8??C to ensure stability. Suitable for use in medicinal chemistry, material science, and as a precursor…

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Description

Description

Methyl 6-bromopyridine-2-carboxylate (CAS No. 26218-75-7) is a high-purity brominated pyridine derivative with the molecular formula C7H6BrNO2. This compound is a versatile building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its structure features a reactive bromine substituent at the 6-position and an ester group at the 2-position, enabling further functionalization via cross-coupling reactions, nucleophilic substitutions, or hydrolysis. Ideal for Suzuki, Stille, or Buchwald-Hartwig couplings, this reagent is supplied as a crystalline solid with ??95% purity (HPLC). Store under inert conditions at 2-8??C to ensure stability. Suitable for use in medicinal chemistry, material science, and as a precursor for heterocyclic scaffolds.

  • CAS No: 26218-75-7
  • Molecular Formula: C7H6BrNO2
  • Molecular Weight: 216.03
  • Exact Mass: 214.95819
  • Monoisotopic Mass: 214.95819
  • IUPAC Name: methyl 6-bromopyridine-2-carboxylate
  • SMILES: COC(=O)C1=NC(=CC=C1)Br
  • Synonyms: 26218-75-7, Methyl 6-bromopyridine-2-carboxylate, Methyl 6-bromo-2-pyridinecarboxylate, DTXSID50584623, DTXCID60535388

Application

Methyl 6-bromopyridine-2-carboxylate is widely used as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and ligands for catalysis. Its bromine moiety facilitates palladium-catalyzed cross-coupling reactions to construct complex pyridine-based architectures. Researchers employ it in the development of kinase inhibitors, receptor modulators, and agrochemicals. The ester group allows straightforward conversion to carboxylic acids or amides, expanding its utility in drug discovery.

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