Description

Description

3-Methoxy-2-methylbenzoyl chloride (CAS No. 24487-91-0) is a high-purity aromatic acyl chloride with the molecular formula C₉H₉ClO₂. This specialized chemical reagent is characterized by its methoxy and methyl substituents on the benzene ring, which enhance its reactivity in electrophilic aromatic substitution and acylation reactions. It is supplied as a clear to pale yellow liquid with a pungent odor, typical of acyl chlorides, and must be stored under inert conditions due to its moisture sensitivity. Ideal for pharmaceutical intermediates, agrochemical synthesis, and advanced material research, this compound is rigorously tested for purity (typically ??95% by GC) and packaged in amber glass bottles under nitrogen to ensure stability. Hazard statements: H314 – Causes severe skin burns and eye damage.

Application

3-Methoxy-2-methylbenzoyl chloride is widely used as a key intermediate in organic synthesis, particularly for constructing complex molecules in pharmaceuticals and agrochemicals. Its acyl chloride group enables efficient Friedel-Crafts acylation reactions to introduce the 3-methoxy-2-methylbenzoyl moiety into target compounds. Researchers also employ it in peptide coupling reactions and as a precursor for photoactive materials. Strict handling under anhydrous conditions is required due to its reactivity with nucleophiles.

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