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Atomfair 5-Fluoropyrimidine-4,6-diol C4H3FN2O2

Description 5-Fluoropyrimidine-4,6-diol (CAS No. 213265-83-9) is a high-purity fluorinated pyrimidine derivative with the molecular formula C4H3FN2O2. This compound, also known by its IUPAC name 5-fluoro-4-hydroxy-1H-pyrimidin-6-one , is a versatile heterocyclic building block widely used in pharmaceutical research, agrochemical development, and organic synthesis. The presence of both hydroxyl and fluorine substituents on the pyrimidine ring makes it a valuable scaffold for designing nucleoside analogs, enzyme inhibitors, and other bioactive molecules. Our product is rigorously tested to ensure ??95% purity (HPLC) and is supplied as a fine white to off-white crystalline powder. Suitable for use in medicinal chemistry, combinatorial libraries, and structure-activity…

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Description

Description

5-Fluoropyrimidine-4,6-diol (CAS No. 213265-83-9) is a high-purity fluorinated pyrimidine derivative with the molecular formula C4H3FN2O2. This compound, also known by its IUPAC name 5-fluoro-4-hydroxy-1H-pyrimidin-6-one, is a versatile heterocyclic building block widely used in pharmaceutical research, agrochemical development, and organic synthesis. The presence of both hydroxyl and fluorine substituents on the pyrimidine ring makes it a valuable scaffold for designing nucleoside analogs, enzyme inhibitors, and other bioactive molecules. Our product is rigorously tested to ensure ??95% purity (HPLC) and is supplied as a fine white to off-white crystalline powder. Suitable for use in medicinal chemistry, combinatorial libraries, and structure-activity relationship (SAR) studies. Store in a cool, dry place at 2-8??C under inert atmosphere for maximum stability.

  • CAS No: 213265-83-9
  • Molecular Formula: C4H3FN2O2
  • Molecular Weight: 130.08
  • Exact Mass: 130.01785550
  • Monoisotopic Mass: 130.01785550
  • IUPAC Name: 5-fluoro-4-hydroxy-1H-pyrimidin-6-one
  • SMILES: C1=NC(=C(C(=O)N1)F)O
  • Synonyms: 5-Fluoropyrimidine-4,6-diol, 106615-61-6, 5-FLUORO-PYRIMIDINE-4,6-DIOL, 5-Fluoro-6-hydroxypyrimidin-4(3H)-one, 4,6-dihydroxy-5-fluoropyrimidine

Application

5-Fluoropyrimidine-4,6-diol serves as a key intermediate in the synthesis of fluorinated nucleoside analogs with potential antiviral and anticancer activities. Researchers utilize this compound to develop novel thymidylate synthase inhibitors for oncology applications. The fluorine substitution enhances metabolic stability in drug candidates while the diol functionality allows for further derivatization. It’s particularly valuable in structure-based drug design targeting DNA/RNA biosynthesis pathways.

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