Description

Description

2,3,5-Trichlorophenylboronic acid (CAS No. 212779-19-6) is a high-purity boronic acid derivative with the molecular formula C₆H₄BCl₃O₂. This compound, also known by its IUPAC name (2,3,5-trichlorophenyl)boronic acid, is a versatile arylboronic acid reagent widely used in Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern synthetic organic chemistry. The presence of three chlorine substituents on the phenyl ring enhances its reactivity and selectivity in palladium-catalyzed transformations.

Our product is rigorously tested to ensure ??95% purity (HPLC) and is supplied as a white to off-white crystalline powder. It is packaged under inert conditions to maintain stability and is ideal for pharmaceutical intermediates, agrochemical synthesis, and materials science research. Storage recommendations include keeping the product in a cool, dry place at 2-8??C under an inert atmosphere to prevent degradation.

Key applications include its use as a building block for the synthesis of complex biaryl compounds, heterocycles, and functionalized polymers. Researchers value this compound for its consistent performance in demanding synthetic protocols.

Application

2,3,5-Trichlorophenylboronic acid is primarily employed in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds between aryl halides and boronic acids. It serves as a key intermediate in pharmaceutical research for constructing drug-like molecules with trichlorophenyl motifs. The compound’s electron-deficient aromatic ring makes it particularly useful in synthesizing agrochemicals and specialty materials requiring halogenated aromatic frameworks.

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