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Atomfair (4-Fluoro-2,3-dimethylphenyl)boronic acid C8H10BFO2
Description (4-Fluoro-2,3-dimethylphenyl)boronic acid (CAS No. 211495-31-7) is a high-purity boronic acid derivative with the molecular formula C8H10BFO2. This compound is a versatile building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds for pharmaceutical and materials science applications. Its unique structure, featuring a fluorine substituent and two methyl groups adjacent to the boronic acid moiety, enhances reactivity and selectivity in coupling reactions. The product is supplied as a white to off-white crystalline powder with ??95% purity (HPLC), ensuring optimal performance in research and industrial processes. Proper storage under inert conditions (argon or nitrogen) at…
Description
Description
(4-Fluoro-2,3-dimethylphenyl)boronic acid (CAS No. 211495-31-7) is a high-purity boronic acid derivative with the molecular formula C8H10BFO2. This compound is a versatile building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds for pharmaceutical and materials science applications. Its unique structure, featuring a fluorine substituent and two methyl groups adjacent to the boronic acid moiety, enhances reactivity and selectivity in coupling reactions. The product is supplied as a white to off-white crystalline powder with ??95% purity (HPLC), ensuring optimal performance in research and industrial processes. Proper storage under inert conditions (argon or nitrogen) at 2-8??C is recommended to maintain stability.
- CAS No: 211495-31-7
- Molecular Formula: C8H10BFO2
- Molecular Weight: 167.98
- Exact Mass: 168.0757879
- Monoisotopic Mass: 168.0757879
- IUPAC Name: (4-fluoro-2,3-dimethylphenyl)boronic acid
- SMILES: B(C1=C(C(=C(C=C1)F)C)C)(O)O
- Synonyms: 211495-31-7, (4-Fluoro-2,3-dimethylphenyl)boronic acid, 4-Fluoro-2,3-dimethylphenylboronic acid, MFCD10699619, 2,3-Dimethyl-4-fluorophenylboronic acid
Application
(4-Fluoro-2,3-dimethylphenyl)boronic acid is widely used in Suzuki-Miyaura cross-coupling reactions to synthesize biaryl compounds for pharmaceutical intermediates and agrochemicals. Its electron-deficient aromatic ring and steric hindrance from methyl groups improve reaction yields in palladium-catalyzed couplings. Researchers also employ it in the development of fluorescent probes and boron-based polymers due to its stable boronic acid functionality.
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