Description

Description

5-Chloro-2-fluoroaniline (CAS No. 2106-05-0) is a high-purity halogenated aniline derivative with the molecular formula C₆H₅ClFN. This aromatic amine is characterized by its chloro- and fluoro-substitutions at the 5- and 2-positions of the aniline ring, respectively, making it a versatile intermediate in organic synthesis and pharmaceutical research. Our product is rigorously tested to ensure >98% purity (HPLC/GC), with low levels of impurities and residual solvents to meet the stringent requirements of research and industrial applications. Supplied as a clear to pale yellow liquid or crystalline solid (depending on storage conditions), it is packaged under inert gas to prevent degradation. Ideal for use in Suzuki couplings, nucleophilic substitutions, and as a building block for agrochemicals, dyes, and active pharmaceutical ingredients (APIs).

Key Specifications:
? CAS: 2106-05-0
? Molecular Weight: 145.56 g/mol
? Melting Point: ~20-25??C (varies with purity)
? Boiling Point: ~220-225??C
? Storage: 2-8??C under nitrogen
? Hazard Codes: Corrosive (GHS05), Toxic (GHS06)

Application

5-Chloro-2-fluoroaniline serves as a critical precursor in the synthesis of advanced pharmaceutical compounds, particularly in the development of kinase inhibitors and antimicrobial agents. Its reactive amino and halogen groups enable efficient cross-coupling reactions (e.g., Buchwald-Hartwig amination) for constructing complex heterocycles. In agrochemical research, it is employed to derivatize herbicides and pesticides, leveraging its halogenated aromatic core for enhanced bioactivity. Additionally, this compound finds utility in material science as a monomer for specialty polymers and dyes.

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