Atomfair

Awaiting product image

Atomfair (2R,4S)-1-tert-Butyl 2-methyl 4-fluoropyrrolidine-1,2-dicarboxylate C11H18FNO4

Description (2R,4S)-1-tert-Butyl 2-methyl 4-fluoropyrrolidine-1,2-dicarboxylate (CAS: 203866-18-6) is a high-purity fluorinated pyrrolidine derivative with the molecular formula C11H18FNO4. This chiral compound is widely utilized in pharmaceutical research and organic synthesis due to its stereospecific configuration and functional versatility. The tert-butyl and methyl ester groups enhance its stability and reactivity, making it an ideal intermediate for the development of bioactive molecules, including protease inhibitors and receptor modulators. Its IUPAC name is 1-O-tert-butyl 2-O-methyl 4-fluoropyrrolidine-1,2-dicarboxylate , and it is available in >98% purity (HPLC) to ensure optimal performance in sensitive applications. Proper storage at 2-8??C under inert conditions is recommended to maintain its…

Category:
Brands:

Description

Description

(2R,4S)-1-tert-Butyl 2-methyl 4-fluoropyrrolidine-1,2-dicarboxylate (CAS: 203866-18-6) is a high-purity fluorinated pyrrolidine derivative with the molecular formula C11H18FNO4. This chiral compound is widely utilized in pharmaceutical research and organic synthesis due to its stereospecific configuration and functional versatility. The tert-butyl and methyl ester groups enhance its stability and reactivity, making it an ideal intermediate for the development of bioactive molecules, including protease inhibitors and receptor modulators. Its IUPAC name is 1-O-tert-butyl 2-O-methyl 4-fluoropyrrolidine-1,2-dicarboxylate, and it is available in >98% purity (HPLC) to ensure optimal performance in sensitive applications. Proper storage at 2-8??C under inert conditions is recommended to maintain its integrity.

  • CAS No: 203866-18-6
  • Molecular Formula: C11H18FNO4
  • Molecular Weight: 247.26
  • Exact Mass: 247.12198622
  • Monoisotopic Mass: 247.12198622
  • IUPAC Name: 1-O-tert-butyl 2-O-methyl 4-fluoropyrrolidine-1,2-dicarboxylate
  • SMILES: CC(C)(C)OC(=O)N1CC(CC1C(=O)OC)F
  • Synonyms: O1-tert-Butyl O2-methyl (2R,4R)-4-fluoropyrrolidine-1,2-dicarboxylate, 1648910-85-3, MFCD07367993, MFCD11054130, MFCD27986950

Application

This compound serves as a key chiral building block in asymmetric synthesis, particularly for the preparation of fluorinated pharmaceuticals and agrochemicals. Its rigid pyrrolidine scaffold and fluorine substitution enable precise stereochemical control in drug design, such as in the synthesis of antiviral or CNS-targeting agents. Researchers also employ it in peptide mimetics and catalyst development due to its bifunctional carboxylate groups.

If you are interested or have any questions, please contact us at support@atomfair.com