Description

Description

5-Methoxy-2-(methylthio)pyrimidin-4-ol (CAS No. 20265-39-8) is a high-purity pyrimidine derivative with the molecular formula C₆H₈N₂O₂S. This compound, also known by its IUPAC name 5-methoxy-2-methylsulfanyl-1H-pyrimidin-6-one, is a versatile heterocyclic building block widely used in pharmaceutical and agrochemical research. Our product is rigorously tested to ensure ??98% purity (HPLC) and is supplied as a fine, off-white to light yellow crystalline powder. It is stable under recommended storage conditions (2-8??C in a dry environment) and is packaged in amber glass vials with argon padding to prevent degradation. This compound is particularly valuable for nucleoside analog synthesis and as a precursor in the development of kinase inhibitors.

Key specifications include: molecular weight of 172.21 g/mol, melting point range of 185-190??C, and solubility in DMSO (50 mg/mL) and methanol (20 mg/mL). The product is characterized by ¹H NMR, ¹³C NMR, and LC-MS to guarantee structural integrity. Available in quantities from 100mg to 100g, with custom bulk packaging options.

Application

5-Methoxy-2-(methylthio)pyrimidin-4-ol serves as a crucial intermediate in medicinal chemistry for the synthesis of antiviral and anticancer agents. Researchers utilize this compound in the development of pyrimidine-based nucleoside analogs that target viral polymerases. In agrochemical applications, it functions as a precursor for crop protection agents due to its heterocyclic reactivity. The methoxy and methylthio substituents make it particularly valuable for structure-activity relationship studies in drug discovery programs.

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