Your cart is currently empty!
Atomfair Sodium chlorodifluoroacetate C2ClF2NaO2
Description Sodium chlorodifluoroacetate (CAS No. 1895-39-2) is a high-purity organofluorine compound with the molecular formula C2ClF2NaO2, widely utilized in synthetic organic chemistry and pharmaceutical research. This white crystalline solid, classified as the sodium salt of chlorodifluoroacetic acid ( IUPAC: sodium;2-chloro-2,2-difluoroacetate ), exhibits exceptional reactivity as a fluorinated building block for nucleophilic substitution reactions. With a molecular weight of 160.47 g/mol, it is soluble in polar solvents like water, DMF, and DMSO, making it ideal for controlled fluorination processes. Our product is rigorously tested to ??98% purity (HPLC) and packaged under inert conditions to ensure stability. Key applications include the synthesis…
Description
Description
Sodium chlorodifluoroacetate (CAS No. 1895-39-2) is a high-purity organofluorine compound with the molecular formula C2ClF2NaO2, widely utilized in synthetic organic chemistry and pharmaceutical research. This white crystalline solid, classified as the sodium salt of chlorodifluoroacetic acid (IUPAC: sodium;2-chloro-2,2-difluoroacetate), exhibits exceptional reactivity as a fluorinated building block for nucleophilic substitution reactions. With a molecular weight of 160.47 g/mol, it is soluble in polar solvents like water, DMF, and DMSO, making it ideal for controlled fluorination processes. Our product is rigorously tested to ??98% purity (HPLC) and packaged under inert conditions to ensure stability. Key applications include the synthesis of fluorinated heterocycles, agrochemical intermediates, and bioactive molecules where selective difluoromethylation is required. Suitable for use under Schlenk line or glovebox conditions due to moisture sensitivity.
- CAS No: 1895-39-2
- Molecular Formula: C2ClF2NaO2
- Molecular Weight: 152.46
- Exact Mass: 151.9452575
- Monoisotopic Mass: 151.9452575
- IUPAC Name: sodium;2-chloro-2,2-difluoroacetate
- SMILES: C(=O)(C(F)(F)Cl)[O-].[Na+]
- Synonyms: Sodium chlorodifluoroacetate, Acetic acid, 2-chloro-2,2-difluoro-, sodium salt (1:1), Acetic acid, chlorodifluoro-, sodium salt, EINECS 217-586-0, DTXSID1062049
Application
Sodium chlorodifluoroacetate serves as a versatile reagent for introducing difluoromethyl (CF2H) and chlorodifluoromethyl (CF2Cl) groups in medicinal chemistry, enabling the modulation of lipophilicity and metabolic stability in drug candidates. It is particularly valuable in the synthesis of fluorinated pyrimidines and quinolones for antimicrobial applications. The compound also finds use in materials science for creating water-repellent coatings and in agrochemical production as a precursor for herbicides with enhanced environmental persistence.
If you are interested or have any questions, please contact us at support@atomfair.com