Description

Description

5-Bromo-2-chloro-1,3-difluorobenzene (CAS No. 176673-72-6) is a high-purity halogenated benzene derivative with the molecular formula C₆H₂BrClF₂. This compound is characterized by its unique substitution pattern, featuring bromo, chloro, and fluoro groups at the 5, 2, and 1,3 positions, respectively, making it a valuable intermediate in organic synthesis and pharmaceutical research. Its precise molecular structure ensures excellent reactivity in cross-coupling reactions, nucleophilic substitutions, and as a building block for advanced materials. Suitable for use in HPLC, GC-MS, and NMR applications, this product is rigorously tested to meet the highest standards of purity and consistency. Packaged under inert gas to ensure stability, it is ideal for researchers requiring reliable and high-quality reagents for complex chemical transformations.

Application

5-Bromo-2-chloro-1,3-difluorobenzene is widely utilized as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty materials. Its halogen-rich structure makes it particularly useful in palladium-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig couplings, enabling the construction of complex aromatic systems. Additionally, this compound serves as a precursor in the development of liquid crystals and organic electronic materials due to its electron-withdrawing properties. Researchers also employ it in the preparation of fluorinated analogs for drug discovery and medicinal chemistry applications.

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