Description

Description

3-Fluorobenzoyl chloride (CAS No. 1711-07-5) is a highly reactive organic compound with the molecular formula C₇H₄ClFO. This aromatic acyl chloride is a colorless to pale yellow liquid under standard conditions, widely used as a key intermediate in organic synthesis and pharmaceutical manufacturing. Its structure features a fluorine atom at the meta position relative to the reactive benzoyl chloride group, making it a valuable building block for introducing fluorinated benzoyl moieties into target molecules.

This compound is packaged under inert gas to ensure stability and is available in high purity grades (>98%) suitable for research and industrial applications. Due to its moisture sensitivity, proper handling under anhydrous conditions is recommended. 3-Fluorobenzoyl chloride is particularly useful in Friedel-Crafts acylation reactions, peptide coupling, and the synthesis of fluorinated pharmaceuticals, agrochemicals, and specialty materials.

Key Specifications:
– CAS Number: 1711-07-5
– Molecular Weight: 158.56 g/mol
– Boiling Point: ~195-198??C
– Density: ~1.33 g/cm³
– Refractive Index: n²⁰_D ~1.543

Application

3-Fluorobenzoyl chloride serves as a versatile reagent in organic synthesis, particularly for introducing fluorinated benzoyl groups into target molecules. It is extensively used in pharmaceutical research for the development of fluorinated drug candidates, where the fluorine atom can enhance metabolic stability and bioavailability. The compound also finds application in materials science for creating specialized polymers and in agrochemical research for synthesizing novel pesticides with improved properties.

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