Atomfair

Awaiting product image

Atomfair 6-(Trifluoromethyl)nicotinamide C7H5F3N2O

Description 6-(Trifluoromethyl)nicotinamide (CAS No. 158062-71-6) is a high-purity fluorinated pyridine derivative with the molecular formula C7H5F3N2O . This compound, also known as 6-(trifluoromethyl)pyridine-3-carboxamide (IUPAC name), is a versatile building block in pharmaceutical and agrochemical research. Its unique trifluoromethyl group enhances lipophilicity and metabolic stability, making it valuable for drug discovery and material science applications. Available in >98% purity (HPLC), this white to off-white crystalline powder is rigorously tested for quality (NMR, LC-MS) and packaged under inert conditions to ensure stability. Suitable for use in Suzuki couplings, amide transformations, and heterocyclic synthesis.

Category:
Brands:

Description

Description

6-(Trifluoromethyl)nicotinamide (CAS No. 158062-71-6) is a high-purity fluorinated pyridine derivative with the molecular formula C7H5F3N2O. This compound, also known as 6-(trifluoromethyl)pyridine-3-carboxamide (IUPAC name), is a versatile building block in pharmaceutical and agrochemical research. Its unique trifluoromethyl group enhances lipophilicity and metabolic stability, making it valuable for drug discovery and material science applications. Available in >98% purity (HPLC), this white to off-white crystalline powder is rigorously tested for quality (NMR, LC-MS) and packaged under inert conditions to ensure stability. Suitable for use in Suzuki couplings, amide transformations, and heterocyclic synthesis.

  • CAS No: 158062-71-6
  • Molecular Formula: C7H5F3N2O
  • Molecular Weight: 190.12
  • Exact Mass: 190.03539727
  • Monoisotopic Mass: 190.03539727
  • IUPAC Name: 6-(trifluoromethyl)pyridine-3-carboxamide
  • SMILES: C1=CC(=NC=C1C(=O)N)C(F)(F)F
  • Synonyms: 6-(trifluoromethyl)nicotinamide, 386715-35-1, DTXSID40380555, DTXCID80331581, 671-269-5

Application

6-(Trifluoromethyl)nicotinamide serves as a key intermediate in the synthesis of bioactive molecules, particularly kinase inhibitors and antimicrobial agents. Its trifluoromethyl group is frequently exploited in medicinal chemistry to improve compound bioavailability. Researchers utilize this scaffold in fragment-based drug design for CNS and oncology targets. The compound also finds use in agrochemical development for crop protection agents.

If you are interested or have any questions, please contact us at support@atomfair.com