Description

Description

Acetylcholine (CAS: 14586-35-7) is a critical endogenous neurotransmitter with the molecular formula C₇H₁₆NO₂⁺ and IUPAC name 2-acetyloxyethyl(trimethyl)azanium. This quaternary ammonium compound plays a pivotal role in both the central and peripheral nervous systems, acting as a key chemical messenger at neuromuscular junctions, autonomic ganglia, and various brain regions. Our high-purity acetylcholine is synthesized under strict quality controls to ensure optimal performance in research applications. Available in multiple formulations and concentrations, this product is ideal for electrophysiology studies, receptor binding assays, and neuropharmacological research. Each batch is rigorously tested for purity (typically >98% by HPLC) and stability, with detailed certificates of analysis provided.

Key synonyms include: Choline acetate, O-Acetylcholine, and Acetyl choline ion (CAS: 51-84-3). Proper storage at -20??C in airtight, light-protected containers is recommended to maintain stability. For research use only; not intended for diagnostic or therapeutic applications.

Application

Acetylcholine is widely utilized in neuroscience research to study cholinergic signaling pathways, synaptic transmission, and cognitive functions. It serves as a critical tool for investigating nicotinic and muscarinic receptor mechanisms in both in vitro and in vivo models. Researchers employ this neurotransmitter in patch-clamp experiments to characterize ion channel activity and in microdialysis studies to assess extracellular levels in brain regions. Its applications extend to drug discovery programs targeting neurodegenerative disorders like Alzheimer’s disease.

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