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Atomfair Benzene, 2,4-dichloro-1-fluoro- 2,4-DCFB C6H3Cl2F

Description 2,4-Dichloro-1-fluorobenzene (CAS No. 1435-48-9) is a high-purity halogenated aromatic compound with the molecular formula C6H3Cl2F . This colorless to pale-yellow liquid is a versatile intermediate in organic synthesis, offering excellent reactivity for nucleophilic substitution and cross-coupling reactions. With a boiling point of approximately 178-180??C and density of 1.45 g/cm3, it is particularly valuable for pharmaceutical, agrochemical, and material science applications. Our product is rigorously tested by HPLC and GC to ensure >98% purity , packaged under nitrogen to prevent degradation. Available in quantities from grams to bulk kilograms with customizable packaging options. Key Features: High reactivity at both chloro…

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Description

Description

2,4-Dichloro-1-fluorobenzene (CAS No. 1435-48-9) is a high-purity halogenated aromatic compound with the molecular formula C6H3Cl2F. This colorless to pale-yellow liquid is a versatile intermediate in organic synthesis, offering excellent reactivity for nucleophilic substitution and cross-coupling reactions. With a boiling point of approximately 178-180??C and density of 1.45 g/cm3, it is particularly valuable for pharmaceutical, agrochemical, and material science applications. Our product is rigorously tested by HPLC and GC to ensure >98% purity, packaged under nitrogen to prevent degradation. Available in quantities from grams to bulk kilograms with customizable packaging options.

Key Features:

  • High reactivity at both chloro and fluoro positions for selective functionalization
  • Ideal building block for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed couplings
  • Stored in amber glass bottles with PTFE-lined caps to ensure stability
  • Comprehensive analytical data (NMR, MS, IR) available upon request
  • CAS No: 1435-48-9
  • Molecular Formula: C6H3Cl2F
  • Molecular Weight: 164.99
  • Exact Mass: 163.9595836
  • Monoisotopic Mass: 163.9595836
  • IUPAC Name: 2,4-dichloro-1-fluorobenzene
  • SMILES: C1=CC(=C(C=C1Cl)Cl)F
  • Synonyms: 1,3-Dichloro-4-fluorobenzene, 2,4-Dichlorofluorobenzene, Benzene, 2,4-dichloro-1-fluoro-, DTXSID30162443, EC 406-160-1

Application

2,4-Dichloro-1-fluorobenzene serves as a critical precursor in pharmaceutical synthesis, particularly for manufacturing active pharmaceutical ingredients (APIs) with dichlorophenyl motifs. Its differential halogen reactivity enables selective derivatization in agrochemical production, forming herbicides and fungicides. The compound is also employed in liquid crystal and polymer synthesis, where its rigid aromatic core and halogen substituents modify material properties.

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