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Atomfair 3-Bromo-4-hydroxyphenylsulfur pentafluoride C6H4BrF5OS

Description 3-Bromo-4-hydroxyphenylsulfur pentafluoride (CAS No. 1426290-12-1) is a highly specialized organosulfur compound with the molecular formula C6H4BrF5OS . This chemical features a unique pentafluorothio ( -SF5) functional group attached to a brominated phenol scaffold, making it a valuable intermediate in advanced synthetic chemistry and materials science. With its IUPAC name 2-bromo-4-(pentafluoro-lambda6-sulfanyl)phenol , this compound exhibits exceptional reactivity due to the electron-withdrawing nature of the -SF5group, which enhances its utility in cross-coupling reactions, pharmaceutical derivatization, and agrochemical synthesis. Provided as a high-purity solid (typically ??95% by GC/HPLC), it is rigorously tested for consistency and stability under controlled conditions. Ideal for researchers…

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Description

Description

3-Bromo-4-hydroxyphenylsulfur pentafluoride (CAS No. 1426290-12-1) is a highly specialized organosulfur compound with the molecular formula C6H4BrF5OS. This chemical features a unique pentafluorothio (-SF5) functional group attached to a brominated phenol scaffold, making it a valuable intermediate in advanced synthetic chemistry and materials science. With its IUPAC name 2-bromo-4-(pentafluoro-lambda6-sulfanyl)phenol, this compound exhibits exceptional reactivity due to the electron-withdrawing nature of the -SF5 group, which enhances its utility in cross-coupling reactions, pharmaceutical derivatization, and agrochemical synthesis. Provided as a high-purity solid (typically ??95% by GC/HPLC), it is rigorously tested for consistency and stability under controlled conditions. Ideal for researchers exploring fluorinated building blocks or sulfur-based ligands, this product is packaged under inert gas to ensure longevity and shipped with comprehensive analytical data (NMR, MS).

  • CAS No: 1426290-12-1
  • Molecular Formula: C6H4BrF5OS
  • Molecular Weight: 299.06
  • Exact Mass: 297.90864
  • Monoisotopic Mass: 297.90864
  • IUPAC Name: 2-bromo-4-(pentafluoro-lambda6-sulfanyl)phenol
  • SMILES: C1=CC(=C(C=C1S(F)(F)(F)(F)F)Br)O
  • Synonyms: 1426290-12-1, 2-Bromo-4-(pentafluorothio)phenol, 3-Bromo-4-hydroxyphenylsulfur pentafluoride, 3-Bromo-4-hydroxyphenylsulphur pentafluoride, 2-bromo-4-(pentafluoro-lambda6-sulfanyl)phenol

Application

3-Bromo-4-hydroxyphenylsulfur pentafluoride serves as a key precursor in the synthesis of SF5-containing aromatic systems, which are increasingly sought after in medicinal chemistry for their metabolic stability and lipophilicity. Its bromophenol moiety enables participation in Pd-catalyzed cross-coupling reactions (e.g., Suzuki-Miyaura), while the -SF5 group acts as a bioisostere for trifluoromethyl (-CF3) in drug design. This compound is also employed in the development of high-performance polymers and liquid crystals, where the -SF5 group imparts unique dielectric properties. Researchers utilize it to create advanced ligands for catalysis or as a probe in 18F-radiolabeling studies due to its structural analogy to fluorinated biomarkers.

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