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Atomfair 1-Piperidinecarboxylic acid, 5-amino-3,3-difluoro-, 1,1-dimethylethyl ester C10H18F2N2O2
Description 1-Piperidinecarboxylic acid, 5-amino-3,3-difluoro-, 1,1-dimethylethyl ester (CAS No. 1392473-32-3) is a high-purity, synthetic organic compound with the molecular formula C10H18F2N2O2. This Boc-protected amino-difluoropiperidine derivative is a valuable building block in medicinal chemistry and pharmaceutical research. The compound features a tert-butyl carbamate (Boc) protecting group, which enhances stability and facilitates selective deprotection during multi-step syntheses. Its unique structural motif, combining a difluorinated piperidine ring with a primary amine functionality, makes it particularly useful for the development of bioactive molecules, including enzyme inhibitors and receptor modulators. Supplied as a white to off-white solid, this reagent is rigorously characterized by NMR, HPLC, and…
Description
Description
1-Piperidinecarboxylic acid, 5-amino-3,3-difluoro-, 1,1-dimethylethyl ester (CAS No. 1392473-32-3) is a high-purity, synthetic organic compound with the molecular formula C10H18F2N2O2. This Boc-protected amino-difluoropiperidine derivative is a valuable building block in medicinal chemistry and pharmaceutical research. The compound features a tert-butyl carbamate (Boc) protecting group, which enhances stability and facilitates selective deprotection during multi-step syntheses. Its unique structural motif, combining a difluorinated piperidine ring with a primary amine functionality, makes it particularly useful for the development of bioactive molecules, including enzyme inhibitors and receptor modulators. Supplied as a white to off-white solid, this reagent is rigorously characterized by NMR, HPLC, and mass spectrometry to ensure ??95% purity, meeting the stringent requirements of advanced research applications.
- CAS No: 1392473-32-3
- Molecular Formula: C10H18F2N2O2
- Molecular Weight: 236.26
- Exact Mass: 236.13363415
- Monoisotopic Mass: 236.13363415
- IUPAC Name: tert-butyl 5-amino-3,3-difluoropiperidine-1-carboxylate
- SMILES: CC(C)(C)OC(=O)N1CC(CC(C1)(F)F)N
- Synonyms: 1258638-82-2, TERT-BUTYL 5-AMINO-3,3-DIFLUOROPIPERIDINE-1-CARBOXYLATE, 1-Piperidinecarboxylic acid, 5-amino-3,3-difluoro-, 1,1-dimethylethyl ester, DTXSID301143260, DTXCID901574865
Application
This Boc-protected 5-amino-3,3-difluoropiperidine derivative serves as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of protease inhibitors and CNS-targeting drugs. Its difluorinated piperidine scaffold contributes to enhanced metabolic stability and bioavailability in drug candidates. Researchers utilize this compound to introduce both fluorine atoms and a protected amine group into molecular architectures during parallel synthesis and combinatorial chemistry approaches.
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