Description

Description

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl cyclopropanecarboxylate (CAS No. 1392277-06-3) is a high-purity organic compound with the molecular formula C₁₂H₉NO₄ and a molecular weight of 231.21 g/mol. This specialized chemical, also known by its IUPAC name (1,3-dioxoisoindol-2-yl) cyclopropanecarboxylate, features a unique cyclopropane carboxylate ester linked to a phthalimide moiety, making it a valuable intermediate in synthetic organic chemistry and pharmaceutical research. Its rigid cyclopropane ring and reactive isoindole-1,3-dione group enable applications in heterocyclic synthesis, peptide modifications, and as a building block for bioactive molecules. Available in >98% purity (HPLC), this compound is supplied as a white to off-white crystalline powder, packaged under inert conditions to ensure stability. Suitable for research and development purposes, it is ideal for scientists exploring novel drug candidates, polymer chemistry, or advanced material science.

Application

1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl cyclopropanecarboxylate serves as a versatile synthon in medicinal chemistry for the design of protease inhibitors and enzyme modulators due to its electrophilic carbonyl groups. Its cyclopropane moiety is exploited in agrochemical research to enhance metabolic stability in active ingredients. Researchers also utilize this compound as a photoactive linker in solid-phase peptide synthesis (SPPS) or as a precursor for functionalized isoindole derivatives.

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