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Atomfair 1,1-Difluoro-3-isocyanocyclobutane C5H5F2N

Description 1,1-Difluoro-3-isocyanocyclobutane (CAS No. 1355328-31-2) is a specialized fluorinated cyclobutane derivative with the molecular formula C5H5F2N. This high-purity compound is designed for advanced research applications, particularly in medicinal chemistry, materials science, and organofluorine synthesis. The presence of both difluoro and isocyano functional groups on the cyclobutane ring offers unique reactivity for cycloadditions, cross-coupling reactions, and as a precursor for heterocyclic scaffolds. Available in rigorously controlled batches (??95% purity by GC/MS), it is supplied in amber glass vials under inert atmosphere to ensure stability. Ideal for researchers exploring fluorinated building blocks or strained ring systems.

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Description

Description

1,1-Difluoro-3-isocyanocyclobutane (CAS No. 1355328-31-2) is a specialized fluorinated cyclobutane derivative with the molecular formula C5H5F2N. This high-purity compound is designed for advanced research applications, particularly in medicinal chemistry, materials science, and organofluorine synthesis. The presence of both difluoro and isocyano functional groups on the cyclobutane ring offers unique reactivity for cycloadditions, cross-coupling reactions, and as a precursor for heterocyclic scaffolds. Available in rigorously controlled batches (??95% purity by GC/MS), it is supplied in amber glass vials under inert atmosphere to ensure stability. Ideal for researchers exploring fluorinated building blocks or strained ring systems.

  • CAS No: 1355328-31-2
  • Molecular Formula: C5H5F2N
  • Molecular Weight: 117.10
  • Exact Mass: 117.03900549
  • Monoisotopic Mass: 117.03900549
  • IUPAC Name: 1,1-difluoro-3-isocyanocyclobutane
  • SMILES: [C-]#[N+]C1CC(C1)(F)F
  • Synonyms: 1,1-difluoro-3-isocyanocyclobutane, 1355328-31-2, 4MF5RCD7WT, SCHEMBL360569, KYWJPXYKFWQBID-UHFFFAOYSA-N

Application

1,1-Difluoro-3-isocyanocyclobutane serves as a versatile intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals. Its strained cyclobutane core enables [2+2] cycloadditions for constructing complex carbocycles, while the isocyanide group facilitates Ugi-type multicomponent reactions. The compound’s fluorine atoms enhance metabolic stability in drug discovery applications. Researchers also utilize it to develop novel fluoropolymers with tailored dielectric properties.

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