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Atomfair Ethyl 4-fluoro-7-methyl-1H-indole-2-carboxylate C12H12FNO2

Description Ethyl 4-fluoro-7-methyl-1H-indole-2-carboxylate (CAS No. 1352906-36-5) is a high-purity fluorinated indole derivative with the molecular formula C12H12FNO2. This compound is a versatile building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. Its unique structure, featuring a fluorine substituent at the 4-position and a methyl group at the 7-position of the indole ring, enhances its reactivity and selectivity in cross-coupling reactions, nucleophilic substitutions, and other transformations. The ethyl carboxylate moiety further expands its utility as an intermediate for ester hydrolysis or amidation. Available in >95% purity (HPLC), this product is rigorously tested for quality, stability,…

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Description

Description

Ethyl 4-fluoro-7-methyl-1H-indole-2-carboxylate (CAS No. 1352906-36-5) is a high-purity fluorinated indole derivative with the molecular formula C12H12FNO2. This compound is a versatile building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. Its unique structure, featuring a fluorine substituent at the 4-position and a methyl group at the 7-position of the indole ring, enhances its reactivity and selectivity in cross-coupling reactions, nucleophilic substitutions, and other transformations. The ethyl carboxylate moiety further expands its utility as an intermediate for ester hydrolysis or amidation. Available in >95% purity (HPLC), this product is rigorously tested for quality, stability, and consistency, making it ideal for research and industrial applications. Packaged under inert gas to ensure longevity, it is supplied in amber glass vials with detailed analytical certificates (COA, MSDS, NMR, and HPLC data).

  • CAS No: 1352906-36-5
  • Molecular Formula: C12H12FNO2
  • Molecular Weight: 221.23
  • Exact Mass: 221.08520679
  • Monoisotopic Mass: 221.08520679
  • IUPAC Name: ethyl 4-fluoro-7-methyl-1H-indole-2-carboxylate
  • SMILES: CCOC(=O)C1=CC2=C(C=CC(=C2N1)C)F
  • Synonyms: Ethyl 4-fluoro-7-methyl-1H-indole-2-carboxylate, 1352906-36-5, SCHEMBL21724772, DB-430200, CS-0146413

Application

Ethyl 4-fluoro-7-methyl-1H-indole-2-carboxylate is a key intermediate in medicinal chemistry for the synthesis of fluorinated indole-based drug candidates, particularly targeting serotonin receptors and kinase inhibitors. Its fluorine atom enhances metabolic stability and bioavailability, making it valuable in preclinical development. Researchers also employ it in material science to design fluorescent probes and optoelectronic materials. In agrochemical research, it serves as a precursor for novel pesticides and herbicides due to its heterocyclic scaffold.

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