Description

Description

5-Bromo-2-hydroxypyridine (CAS No. 13466-38-1) is a high-purity heterocyclic organic compound with the molecular formula C₅H₄BrNO. This brominated pyridine derivative is a versatile building block in pharmaceutical, agrochemical, and materials science research. Its IUPAC name, 5-bromo-1H-pyridin-2-one, reflects its structural features: a pyridine ring substituted with a bromine atom at the 5-position and a hydroxyl group at the 2-position.

Our product is rigorously tested to ensure ??98% purity (HPLC) and is supplied as a white to off-white crystalline powder. It is packaged under inert conditions to guarantee stability and longevity. Ideal for nucleophilic substitution reactions, metal-catalyzed cross-couplings, and as a precursor for more complex heterocycles, this compound is a must-have for medicinal chemists and researchers developing novel bioactive molecules.

Key applications include its use in Suzuki-Miyaura couplings, Buchwald-Hartwig aminations, and as a scaffold for kinase inhibitors. Store in a cool, dry place at 2-8??C, protected from light and moisture.

Application

5-Bromo-2-hydroxypyridine serves as a key intermediate in the synthesis of pharmaceutical compounds, particularly kinase inhibitors and antimicrobial agents. Its reactive bromine and hydroxyl groups enable facile functionalization for structure-activity relationship studies. Researchers utilize this compound in palladium-catalyzed cross-coupling reactions to construct complex heteroaromatic systems. It also finds use in material science as a ligand for metal-organic frameworks (MOFs) and in agrochemical research for developing novel crop protection agents.

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