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Atomfair 4-Bromo-2-fluoro-3-methylpyridine C6H5BrFN

Description 4-Bromo-2-fluoro-3-methylpyridine (CAS No. 128071-79-4) is a high-purity halogenated pyridine derivative with the molecular formula C6H5BrFN . This compound is a valuable heterocyclic building block for pharmaceutical, agrochemical, and materials science research. Its structure features a bromo substituent at the 4-position, a fluoro group at the 2-position, and a methyl group at the 3-position of the pyridine ring, offering versatile reactivity for cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitutions. Available in ??95% purity (GC), it is supplied in sealed containers under inert gas to ensure stability. Ideal for high-throughput screening , medicinal chemistry , and catalyst development . Store…

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Description

Description

4-Bromo-2-fluoro-3-methylpyridine (CAS No. 128071-79-4) is a high-purity halogenated pyridine derivative with the molecular formula C6H5BrFN. This compound is a valuable heterocyclic building block for pharmaceutical, agrochemical, and materials science research. Its structure features a bromo substituent at the 4-position, a fluoro group at the 2-position, and a methyl group at the 3-position of the pyridine ring, offering versatile reactivity for cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitutions. Available in ??95% purity (GC), it is supplied in sealed containers under inert gas to ensure stability. Ideal for high-throughput screening, medicinal chemistry, and catalyst development. Store at 2-8??C in a dry environment.

  • CAS No: 128071-79-4
  • Molecular Formula: C6H5BrFN
  • Molecular Weight: 190.01
  • Exact Mass: 188.95894
  • Monoisotopic Mass: 188.95894
  • IUPAC Name: 4-bromo-2-fluoro-3-methylpyridine
  • SMILES: CC1=C(C=CN=C1F)Br
  • Synonyms: 4-Bromo-2-fluoro-3-methylpyridine, 128071-79-4, DTXSID00628748, DTXCID20579501, 855-090-1

Application

4-Bromo-2-fluoro-3-methylpyridine serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor development. Its halogenated pyridine core is utilized in crop protection chemicals to modify bioactivity. Researchers also employ it in PET radioligand synthesis due to the fluorine moiety’s isotopic labeling potential. The methyl group enhances steric tuning in coordination chemistry.

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