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Atomfair 3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde, (R)-(+)- (R)-Garner Aldehyde C11H19NO4

Description 3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde, (R)-(+)- (CAS No. 127589-93-9) is a high-purity chiral building block widely used in asymmetric synthesis and pharmaceutical research. This compound, with the molecular formula C11H19NO4, is a protected form of (R)-Garner’s aldehyde, offering exceptional stereochemical control for the synthesis of amino acids, peptides, and other bioactive molecules. The tert-butyloxycarbonyl (Boc) and dimethyloxazolidine groups provide robust protection for sensitive functional groups during multi-step synthetic processes. With an IUPAC name of tert-butyl (4R)-4-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate , this reagent is rigorously tested for purity (typically ??95% by HPLC) and stored under optimal conditions to ensure stability. Ideal for researchers requiring enantiomerically pure intermediates,…

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Description

Description

3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde, (R)-(+)- (CAS No. 127589-93-9) is a high-purity chiral building block widely used in asymmetric synthesis and pharmaceutical research. This compound, with the molecular formula C11H19NO4, is a protected form of (R)-Garner’s aldehyde, offering exceptional stereochemical control for the synthesis of amino acids, peptides, and other bioactive molecules. The tert-butyloxycarbonyl (Boc) and dimethyloxazolidine groups provide robust protection for sensitive functional groups during multi-step synthetic processes. With an IUPAC name of tert-butyl (4R)-4-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate, this reagent is rigorously tested for purity (typically ??95% by HPLC) and stored under optimal conditions to ensure stability. Ideal for researchers requiring enantiomerically pure intermediates, this product is supplied in amber glass vials with detailed analytical certificates (CoA) including NMR, MS, and chiral HPLC data.

  • CAS No: 127589-93-9
  • Molecular Formula: C11H19NO4
  • Molecular Weight: 229.27
  • Exact Mass: 229.13140809
  • Monoisotopic Mass: 229.13140809
  • IUPAC Name: tert-butyl (4R)-4-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
  • SMILES: CC1(N([C@H](CO1)C=O)C(=O)OC(C)(C)C)C
  • Synonyms: 95715-87-0, (R)-Garner Aldehyde, (R)-Garner’s aldehyde, Garner’s aldehyde R-form [MI], UPK623LV60

Application

This (R)-(+)-enantiomer of Garner’s aldehyde is a key intermediate in the synthesis of non-natural amino acids and peptidomimetics, particularly for drug discovery and medicinal chemistry applications. It serves as a versatile precursor for the preparation of chiral ??-amino alcohols and heterocyclic compounds. The aldehyde functionality allows for further elaboration via reductive amination or nucleophilic addition reactions, making it valuable for constructing complex molecular architectures.

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