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Atomfair alpha-Me-D-Phe(3-Br)-OH.H2O C10H12BrNO2

Description alpha-Me-D-Phe(3-Br)-OH.H2O (CAS No. 1212117-73-1) is a high-purity, non-natural amino acid derivative designed for advanced research applications. This compound, with the molecular formula C10H12BrNO2, is a chiral building block featuring a 3-bromophenyl group and a methyl substitution at the alpha-position, enhancing its utility in peptide modification and medicinal chemistry. Its IUPAC name, 2-amino-3-(3-bromophenyl)-2-methylpropanoic acid , reflects its precise structural configuration. Ideal for solid-phase peptide synthesis (SPPS), this product is supplied as a hydrate to ensure stability and solubility. Rigorous QC protocols guarantee ??95% purity (HPLC), making it suitable for drug discovery, proteomics, and bioconjugation studies. Store desiccated at -20??C for…

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Description

Description

alpha-Me-D-Phe(3-Br)-OH.H2O (CAS No. 1212117-73-1) is a high-purity, non-natural amino acid derivative designed for advanced research applications. This compound, with the molecular formula C10H12BrNO2, is a chiral building block featuring a 3-bromophenyl group and a methyl substitution at the alpha-position, enhancing its utility in peptide modification and medicinal chemistry. Its IUPAC name, 2-amino-3-(3-bromophenyl)-2-methylpropanoic acid, reflects its precise structural configuration. Ideal for solid-phase peptide synthesis (SPPS), this product is supplied as a hydrate to ensure stability and solubility. Rigorous QC protocols guarantee ??95% purity (HPLC), making it suitable for drug discovery, proteomics, and bioconjugation studies. Store desiccated at -20??C for long-term stability.

  • CAS No: 1212117-73-1
  • Molecular Formula: C10H12BrNO2
  • Molecular Weight: 258.11
  • Exact Mass: 257.00514
  • Monoisotopic Mass: 257.00514
  • IUPAC Name: 2-amino-3-(3-bromophenyl)-2-methylpropanoic acid
  • SMILES: CC(CC1=CC(=CC=C1)Br)(C(=O)O)N
  • Synonyms: alpha-Me-D-Phe(3-Br)-OH.H2O, 2-amino-3-(3-bromophenyl)-2-methylpropanoic acid, SCHEMBL10680474

Application

alpha-Me-D-Phe(3-Br)-OH.H2O serves as a versatile scaffold in peptide engineering, enabling the incorporation of steric hindrance and bromo-functionalized aromatic moieties into bioactive sequences. Its D-configuration and methyl group enhance metabolic stability in peptidomimetic drug candidates. Researchers utilize this derivative to study structure-activity relationships (SAR) in GPCR-targeting peptides or as a heavy-atom label for X-ray crystallography. The bromophenyl group also facilitates click chemistry modifications for probe development.

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