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Atomfair Methyl 4-bromo-2,5-difluorobenzoate C8H5BrF2O2

Description Methyl 4-bromo-2,5-difluorobenzoate (CAS No. 1193162-21-8) is a high-purity fluorinated benzoate ester with the molecular formula C8H5BrF2O2. This compound is a versatile building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its structure features a bromine substituent at the 4-position and fluorine atoms at the 2- and 5-positions, making it a valuable intermediate for cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig couplings. The methyl ester group enhances solubility in organic solvents, facilitating downstream transformations. Supplied as a white to off-white crystalline solid with ??95% purity (HPLC), it is rigorously tested for consistency and stability. Store in a cool,…

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Description

Description

Methyl 4-bromo-2,5-difluorobenzoate (CAS No. 1193162-21-8) is a high-purity fluorinated benzoate ester with the molecular formula C8H5BrF2O2. This compound is a versatile building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its structure features a bromine substituent at the 4-position and fluorine atoms at the 2- and 5-positions, making it a valuable intermediate for cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig couplings. The methyl ester group enhances solubility in organic solvents, facilitating downstream transformations. Supplied as a white to off-white crystalline solid with ??95% purity (HPLC), it is rigorously tested for consistency and stability. Store in a cool, dry place under inert atmosphere to maintain optimal quality. Suitable for research use only (RUO).

  • CAS No: 1193162-21-8
  • Molecular Formula: C8H5BrF2O2
  • Molecular Weight: 251.02
  • Exact Mass: 249.94410
  • Monoisotopic Mass: 249.94410
  • IUPAC Name: methyl 4-bromo-2,5-difluorobenzoate
  • SMILES: COC(=O)C1=CC(=C(C=C1F)Br)F
  • Synonyms: methyl 4-bromo-2,5-difluorobenzoate, 1193162-21-8, 816-540-2, Benzoic acid, 4-bromo-2,5-difluoro-, methyl ester, MFCD23713110

Application

Methyl 4-bromo-2,5-difluorobenzoate is widely used as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and specialty chemicals. Its bromo and fluoro substituents enable selective functionalization via metal-catalyzed cross-coupling reactions. Researchers employ this compound in the development of fluorinated drug candidates, leveraging its metabolic stability and bioavailability-enhancing properties. It is also utilized in materials science for designing liquid crystals and polymers with tailored electronic properties.

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