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Atomfair (S)-22-Carboxy-1-[(2,5-dioxopyrrolidin-1-yl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontan-41-oic Acid C39H66N4O15

Description (S)-22-Carboxy-1-[(2,5-dioxopyrrolidin-1-yl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontan-41-oic Acid (CAS No. 1169630-40-3) is a high-purity, synthetic organic compound with the molecular formula C39H66N4O15. This specialized reagent features a complex structure incorporating multiple functional groups, including carboxylic acids, amides, and a reactive N-hydroxysuccinimide (NHS) ester moiety. The IUPAC name, 18-[[1-carboxy-4-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrolidin-1-yl)oxy-2-oxoethoxy]ethoxy]ethylamino]-2-oxoethoxy]ethoxy]ethylamino]-4-oxobutyl]amino]-18-oxooctadecanoic acid , reflects its intricate polyether and peptide-like architecture. Supplied as a lyophilized powder or in solution, this compound is ideal for bioconjugation, crosslinking, and protein modification applications. It is characterized by HPLC purity ??95% and is stored at -20??C to maintain stability. Synonyms include MFCD32704903, SCHEMBL2151921, and SY322938.

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Description

Description

(S)-22-Carboxy-1-[(2,5-dioxopyrrolidin-1-yl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontan-41-oic Acid (CAS No. 1169630-40-3) is a high-purity, synthetic organic compound with the molecular formula C39H66N4O15. This specialized reagent features a complex structure incorporating multiple functional groups, including carboxylic acids, amides, and a reactive N-hydroxysuccinimide (NHS) ester moiety. The IUPAC name, 18-[[1-carboxy-4-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrolidin-1-yl)oxy-2-oxoethoxy]ethoxy]ethylamino]-2-oxoethoxy]ethoxy]ethylamino]-4-oxobutyl]amino]-18-oxooctadecanoic acid, reflects its intricate polyether and peptide-like architecture. Supplied as a lyophilized powder or in solution, this compound is ideal for bioconjugation, crosslinking, and protein modification applications. It is characterized by HPLC purity ??95% and is stored at -20??C to maintain stability. Synonyms include MFCD32704903, SCHEMBL2151921, and SY322938.

  • CAS No: 1169630-40-3
  • Molecular Formula: C39H66N4O15
  • Molecular Weight: 831.0
  • Exact Mass: 830.45246741
  • Monoisotopic Mass: 830.45246741
  • IUPAC Name: 18-[[1-carboxy-4-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrolidin-1-yl)oxy-2-oxoethoxy]ethoxy]ethylamino]-2-oxoethoxy]ethoxy]ethylamino]-4-oxobutyl]amino]-18-oxooctadecanoic acid
  • SMILES: C1CC(=O)N(C1=O)OC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCC(C(=O)O)NC(=O)CCCCCCCCCCCCCCCCC(=O)O
  • Synonyms: MFCD32704903, SCHEMBL2151921, SY322938, (S)-22-Carboxy-1-[(2,5-dioxopyrrolidin-1-yl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontan-41-oic Acid

Application

This compound is primarily used as a heterobifunctional crosslinker for conjugating biomolecules such as proteins, peptides, or antibodies via its NHS ester and carboxylic acid groups. Its extended polyethylene glycol (PEG) spacer arm enables controlled distance between conjugated molecules, reducing steric hindrance. Applications include antibody-drug conjugate (ADC) development, surface immobilization for biosensors, and the creation of custom bioconjugates for diagnostic assays. The NHS ester reacts efficiently with primary amines at physiological pH, while the terminal carboxyl group can be activated for further coupling to hydroxyl or amine-containing molecules.

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