Description

Description

4-Bromo-1-fluoro-2-iodobenzene (CAS No. 116272-41-4) is a high-purity halogenated aromatic compound with the molecular formula C₆H₃BrFI. This versatile intermediate is widely used in organic synthesis, pharmaceutical research, and material science applications. Its unique combination of bromo, fluoro, and iodo substituents on the benzene ring makes it a valuable building block for cross-coupling reactions, such as Suzuki, Stille, and Sonogashira couplings.

Our product is rigorously tested to ensure exceptional quality, with purity levels typically exceeding 97% (GC analysis). It is supplied as a crystalline solid at room temperature, packaged under inert atmosphere to maintain stability. The compound’s molecular weight is 300.90 g/mol, with a melting point range of 45-50??C.

Special handling precautions are recommended due to the light-sensitive nature of the iodo substituent. Store in amber glass containers at 2-8??C under inert atmosphere for optimal shelf life. Technical data sheets and certificates of analysis are available upon request.

Application

4-Bromo-1-fluoro-2-iodobenzene serves as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of fluorinated drug candidates. The compound’s multiple halogen sites enable sequential functionalization through selective cross-coupling reactions. Researchers utilize this building block in material science for creating specialized liquid crystals and organic electronic materials. Its unique substitution pattern also makes it valuable for studying structure-activity relationships in medicinal chemistry programs.

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