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Atomfair (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine C9H9F2N

Description (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (CAS No. 1156491-10-9) is a high-purity chiral cyclopropane derivative with the molecular formula C9H9F2N. This compound features a stereospecific (1R,2S) configuration and a 3,4-difluorophenyl substituent, making it a valuable intermediate in pharmaceutical and agrochemical research. Its rigid cyclopropane ring and fluorine substitution enhance metabolic stability and binding affinity, ideal for drug discovery applications. Available in >98% purity by HPLC, this product is rigorously tested for quality and consistency, ensuring reliable performance in synthetic and medicinal chemistry workflows. Suitable for use in asymmetric synthesis, catalysis, and as a building block for bioactive molecules.

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Description

Description

(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (CAS No. 1156491-10-9) is a high-purity chiral cyclopropane derivative with the molecular formula C9H9F2N. This compound features a stereospecific (1R,2S) configuration and a 3,4-difluorophenyl substituent, making it a valuable intermediate in pharmaceutical and agrochemical research. Its rigid cyclopropane ring and fluorine substitution enhance metabolic stability and binding affinity, ideal for drug discovery applications. Available in >98% purity by HPLC, this product is rigorously tested for quality and consistency, ensuring reliable performance in synthetic and medicinal chemistry workflows. Suitable for use in asymmetric synthesis, catalysis, and as a building block for bioactive molecules.

  • CAS No: 1156491-10-9
  • Molecular Formula: C9H9F2N
  • Molecular Weight: 169.17
  • Exact Mass: 169.07030562
  • Monoisotopic Mass: 169.07030562
  • IUPAC Name: (1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine
  • SMILES: C1[C@H]([C@@H]1N)C2=CC(=C(C=C2)F)F
  • Synonyms: 220352-38-5, (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine, OIY4B72TG1, (1R,2S)-2-(3,4-difluorophenyl)cyclopropylamine, UNII-OIY4B72TG1

Application

(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is a key chiral synthon in the development of CNS-active pharmaceuticals, particularly for serotonin and dopamine receptor modulators. Its structural rigidity and fluorine substitution make it a preferred scaffold for optimizing drug potency and pharmacokinetics. Researchers also utilize this compound in asymmetric catalysis and as a precursor for agrochemical active ingredients.

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