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Atomfair (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)propanoate Boc-L-Tyr(Tf)-OMe C16H20F3NO7S

Description (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)propanoate (CAS No. 112766-18-4) is a high-purity, synthetic amino acid derivative designed for advanced research applications. With the molecular formula C16H20F3NO7S , this compound features a chiral (S)-configuration, a tert -butoxycarbonyl (Boc) protecting group, and a trifluoromethylsulfonyl (Tf) ester moiety, making it a versatile intermediate in peptide synthesis and medicinal chemistry. Its precise structure, methyl (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-(trifluoromethylsulfonyloxy)phenyl]propanoate , ensures optimal reactivity in coupling reactions and selective deprotection strategies. Packaged under inert conditions to guarantee stability, this product is ideal for pharmaceutical development, asymmetric synthesis, and proteomics research. Available in quantities from milligrams to bulk scales, with certificates of analysis…

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Description

Description

(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)propanoate (CAS No. 112766-18-4) is a high-purity, synthetic amino acid derivative designed for advanced research applications. With the molecular formula C16H20F3NO7S, this compound features a chiral (S)-configuration, a tert-butoxycarbonyl (Boc) protecting group, and a trifluoromethylsulfonyl (Tf) ester moiety, making it a versatile intermediate in peptide synthesis and medicinal chemistry. Its precise structure, methyl (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-(trifluoromethylsulfonyloxy)phenyl]propanoate, ensures optimal reactivity in coupling reactions and selective deprotection strategies. Packaged under inert conditions to guarantee stability, this product is ideal for pharmaceutical development, asymmetric synthesis, and proteomics research. Available in quantities from milligrams to bulk scales, with certificates of analysis (CoA) and HPLC/GC-MS purity data upon request.

  • CAS No: 112766-18-4
  • Molecular Formula: C16H20F3NO7S
  • Molecular Weight: 427.4
  • Exact Mass: 427.09125764
  • Monoisotopic Mass: 427.09125764
  • IUPAC Name: methyl (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-(trifluoromethylsulfonyloxy)phenyl]propanoate
  • SMILES: CC(C)(C)OC(=O)N[C@@H](CC1=CC=C(C=C1)OS(=O)(=O)C(F)(F)F)C(=O)OC
  • Synonyms: 112766-18-4, Boc-L-Tyr(Tf)-OMe, (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)propanoate, Methyl 2-(tert-butoxycarbonylaMino)-3-(4-(trifluoroMethylsulfonyloxy)phenyl)propanoate, methyl (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-(trifluoromethylsulfonyloxy)phenyl]propanoate

Application

This compound serves as a key chiral building block in the synthesis of modified peptides and peptidomimetics, particularly for introducing tyrosine derivatives with sulfonyl ester functionalities. It is widely used in medicinal chemistry for the development of protease inhibitors and receptor-targeted therapeutics due to its triflate leaving group, enabling nucleophilic aromatic substitution. Researchers also employ it in solid-phase peptide synthesis (SPPS) to incorporate protected tyrosine analogs with orthogonal deprotection capabilities.

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