Description

Description

1-(2-Chloroethyl)piperidine-4-carbonitrile (CAS No. 108890-51-3) is a high-purity organic compound with the molecular formula C₈H₁₃ClN₂. This specialized chemical features a piperidine core functionalized with a chloroethyl group at the nitrogen position and a nitrile group at the 4-position, making it a versatile intermediate for pharmaceutical and agrochemical synthesis. With a molecular weight of 172.66 g/mol, this compound is supplied as a clear to pale-yellow liquid or solid, depending on storage conditions. It is characterized by its unique reactivity profile, enabling use in nucleophilic substitution reactions, cyclizations, and as a precursor for heterocyclic scaffolds. Our product is rigorously tested to ensure ??95% purity (HPLC) and is packaged under inert gas to maintain stability. Ideal for medicinal chemistry research, this building block is particularly valuable in the development of CNS-targeting agents and enzyme inhibitors. Proper handling requires PPE due to potential skin/eye irritation.

Application

This compound serves as a key intermediate in the synthesis of pharmacologically active piperidine derivatives, particularly in developing dopamine receptor modulators. Researchers utilize its reactive chloroethyl and nitrile groups for constructing complex heterocycles via alkylation or cyclization reactions. The molecule’s structural features make it valuable for probing sigma receptor interactions in neurological studies. It has shown utility in creating analogs for potential antipsychotic and analgesic applications.

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