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Atomfair 8-Quinolinyl trifluoromethanesulfonate 8-Quinolinyl triflate C10H6F3NO3S

Description 8-Quinolinyl trifluoromethanesulfonate (CAS No. 108530-08-1) is a high-purity organic compound with the molecular formula C10H6F3NO3S . This specialized reagent, also known as quinolin-8-yl trifluoromethanesulfonate or 8-Quinolinyl triflate , is widely used in synthetic organic chemistry and pharmaceutical research. The compound features a quinoline backbone functionalized with a reactive trifluoromethanesulfonate (triflate) group, making it an excellent intermediate for nucleophilic substitution reactions, cross-coupling reactions, and as a precursor for more complex heterocyclic systems. Our product is rigorously tested to ensure ??98% purity (HPLC) and is supplied in sealed containers under inert atmosphere to guarantee stability. Ideal for researchers developing novel catalysts,…

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Description

Description

8-Quinolinyl trifluoromethanesulfonate (CAS No. 108530-08-1) is a high-purity organic compound with the molecular formula C10H6F3NO3S. This specialized reagent, also known as quinolin-8-yl trifluoromethanesulfonate or 8-Quinolinyl triflate, is widely used in synthetic organic chemistry and pharmaceutical research. The compound features a quinoline backbone functionalized with a reactive trifluoromethanesulfonate (triflate) group, making it an excellent intermediate for nucleophilic substitution reactions, cross-coupling reactions, and as a precursor for more complex heterocyclic systems. Our product is rigorously tested to ensure ??98% purity (HPLC) and is supplied in sealed containers under inert atmosphere to guarantee stability. Ideal for researchers developing novel catalysts, ligands, or bioactive molecules in medicinal chemistry.

  • CAS No: 108530-08-1
  • Molecular Formula: C10H6F3NO3S
  • Molecular Weight: 277.22
  • Exact Mass: 277.00204871
  • Monoisotopic Mass: 277.00204871
  • IUPAC Name: quinolin-8-yl trifluoromethanesulfonate
  • SMILES: C1=CC2=C(C(=C1)OS(=O)(=O)C(F)(F)F)N=CC=C2
  • Synonyms: 8-Quinolinyl trifluoromethanesulfonate, 622-900-8, quinolin-8-yl trifluoromethanesulfonate, 108530-08-1, 8-Quinolinyl triflate

Application

8-Quinolinyl trifluoromethanesulfonate serves as a versatile building block in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions for constructing complex heteroaromatic systems. The triflate group’s excellent leaving group properties enable efficient nucleophilic aromatic substitutions in pharmaceutical intermediate synthesis. Researchers utilize this compound to develop novel quinoline-based ligands for transition metal catalysis and as a precursor for fluorescent probes in biochemical studies.

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