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Atomfair DL-alpha-Methylleucine C7H15NO2

Description DL-alpha-Methylleucine (CAS No. 105743-53-1) is a non-proteinogenic amino acid with the molecular formula C7H15NO2. This racemic compound, also known as 2-amino-2,4-dimethylpentanoic acid, is a valuable chiral building block in organic synthesis and pharmaceutical research. Its unique structure, featuring a quaternary alpha-carbon and two methyl groups, makes it an interesting candidate for studying steric effects in peptide design and enzyme inhibition. The compound is supplied as a white to off-white crystalline powder with high purity (>98%) and is suitable for a wide range of research applications. DL-alpha-Methylleucine is particularly useful in medicinal chemistry for developing novel peptide mimetics and investigating…

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Description

Description

DL-alpha-Methylleucine (CAS No. 105743-53-1) is a non-proteinogenic amino acid with the molecular formula C7H15NO2. This racemic compound, also known as 2-amino-2,4-dimethylpentanoic acid, is a valuable chiral building block in organic synthesis and pharmaceutical research. Its unique structure, featuring a quaternary alpha-carbon and two methyl groups, makes it an interesting candidate for studying steric effects in peptide design and enzyme inhibition. The compound is supplied as a white to off-white crystalline powder with high purity (>98%) and is suitable for a wide range of research applications. DL-alpha-Methylleucine is particularly useful in medicinal chemistry for developing novel peptide mimetics and investigating metabolic pathways involving branched-chain amino acids. Proper storage at 2-8??C ensures long-term stability of this sensitive compound.

  • CAS No: 105743-53-1
  • Molecular Formula: C7H15NO2
  • Molecular Weight: 145.20
  • Exact Mass: 145.110278721
  • Monoisotopic Mass: 145.110278721
  • IUPAC Name: 2-amino-2,4-dimethylpentanoic acid
  • SMILES: CC(C)CC(C)(C(=O)O)N
  • Synonyms: DL-alpha-Methylleucine, 144-24-1, 2-amino-2,4-dimethylpentanoic acid, H-alpha-Me-DL-Leu-OH, T2MJ2EEP1K

Application

DL-alpha-Methylleucine serves as a crucial intermediate in peptide modification studies, where its sterically hindered structure helps investigate conformational constraints. Researchers utilize this compound to develop enzyme inhibitors targeting leucine-metabolizing enzymes in metabolic disorder research. The methylated alpha-carbon makes it particularly valuable for studying structure-activity relationships in medicinal chemistry applications.

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