Atomfair 1-(oxan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole C14H23BN2O3

Description 1-(Oxan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS: 1003846-21-6) is a high-purity boronic ester derivative designed for advanced synthetic and catalytic applications in organic chemistry and pharmaceutical research. With the molecular formula C14H23BN2O3, this compound features a pyrazole core functionalized with a tetramethyl dioxaborolane group, offering exceptional stability and reactivity in cross-coupling reactions such as Suzuki-Miyaura couplings. The oxane (tetrahydropyran) substitution enhances solubility in organic solvents, making it ideal for homogeneous catalysis. This reagent is rigorously tested for quality (??95% purity by HPLC) and is supplied in moisture-resistant packaging to ensure long-term stability. Suitable for use in medicinal chemistry, materials science, and agrochemical development.

Description

1-(Oxan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS: 1003846-21-6) is a high-purity boronic ester derivative designed for advanced synthetic and catalytic applications in organic chemistry and pharmaceutical research. With the molecular formula C₁₄H₂₃BN₂O₃, this compound features a pyrazole core functionalized with a tetramethyl dioxaborolane group, offering exceptional stability and reactivity in cross-coupling reactions such as Suzuki-Miyaura couplings. The oxane (tetrahydropyran) substitution enhances solubility in organic solvents, making it ideal for homogeneous catalysis. This reagent is rigorously tested for quality (??95% purity by HPLC) and is supplied in moisture-resistant packaging to ensure long-term stability. Suitable for use in medicinal chemistry, materials science, and agrochemical development.

CAS No: 1003846-21-6
Molecular Formula: C14H23BN2O3
Molecular Weight: 278.16
Exact Mass: 278.1801728
Monoisotopic Mass: 278.1801728
IUPAC Name: 1-(oxan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole
SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CN(N=C2)C3CCCCO3
Synonyms: 1003846-21-6, DTXSID20679570, 1-(Oxan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, DTXCID30630319, 817-729-2

Application

This boronic ester is widely employed as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds in pharmaceutical research. Its stability under aerobic conditions makes it advantageous for catalytic systems requiring mild conditions. The compound is also utilized in the development of boron-containing probes for chemical biology studies. Researchers value its compatibility with diverse functional groups in complex molecular architectures.

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