Description

Description

2,3-Difluoro-4-bromonitrobenzene (CAS No. 1003708-24-4) is a high-purity halogenated nitrobenzene derivative with the molecular formula C₆H₂BrF₂NO₂. This compound, also known by its IUPAC name 1-bromo-2,3-difluoro-4-nitrobenzene, is a valuable building block in organic synthesis and pharmaceutical research. Its unique structure, featuring bromine, fluorine, and nitro functional groups on an aromatic ring, makes it an essential intermediate for the development of agrochemicals, pharmaceuticals, and specialty materials.

Our product is rigorously tested to ensure >98% purity (HPLC) and is supplied as a crystalline solid with excellent batch-to-batch consistency. Proper storage recommendations include protection from light and moisture at 2-8??C. Available in research quantities from milligrams to kilogram scale, this compound is ideal for Suzuki couplings, nucleophilic aromatic substitutions, and other advanced synthetic transformations.

Application

2,3-Difluoro-4-bromonitrobenzene serves as a versatile intermediate in pharmaceutical synthesis, particularly for creating fluorinated drug candidates with enhanced metabolic stability. The compound’s orthogonal reactivity allows selective modification of either the bromine or nitro group in Pd-catalyzed cross-couplings or reduction reactions. Researchers utilize this building block to develop novel materials with unique electronic properties for organic electronics applications. Its fluorine substitution pattern makes it valuable for studying structure-activity relationships in medicinal chemistry programs.

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