Atomfair 2-Chloro-1,3,2-dioxaphospholane 2-oxide C2H4ClO3P

Description 2-Chloro-1,3,2-dioxaphospholane 2-oxide (CAS No. 6609-64-9) is a highly specialized organophosphorus compound with the molecular formula C2H4ClO3P . This cyclic phosphonate ester is a versatile intermediate in organic synthesis, particularly in the preparation of flame retardants, pharmaceuticals, and agrochemicals. Its IUPAC name, 2-chloro-1,3,2??5-dioxaphospholane 2-oxide , reflects its unique heterocyclic structure, which features a phosphorus center bonded to chlorine and oxygen functionalities. The compound is characterized by its high reactivity, making it valuable for phosphorylation reactions and as a precursor for modified nucleotides or phosphoramidites. Available in high purity grades, this chemical is supplied with comprehensive analytical data (including1H NMR,13C NMR,…

Description

2-Chloro-1,3,2-dioxaphospholane 2-oxide (CAS No. 6609-64-9) is a highly specialized organophosphorus compound with the molecular formula C₂H₄ClO₃P. This cyclic phosphonate ester is a versatile intermediate in organic synthesis, particularly in the preparation of flame retardants, pharmaceuticals, and agrochemicals. Its IUPAC name, 2-chloro-1,3,2??⁵-dioxaphospholane 2-oxide, reflects its unique heterocyclic structure, which features a phosphorus center bonded to chlorine and oxygen functionalities. The compound is characterized by its high reactivity, making it valuable for phosphorylation reactions and as a precursor for modified nucleotides or phosphoramidites. Available in high purity grades, this chemical is supplied with comprehensive analytical data (including ¹H NMR, ¹³C NMR, and MS) to ensure consistency for research and industrial applications. Store under inert conditions to maintain stability.

CAS No: 6609-64-9
Molecular Formula: C2H4ClO3P
Molecular Weight: 142.48
Exact Mass: 141.9586587
Monoisotopic Mass: 141.9586587
IUPAC Name: 2-chloro-1,3,2lambda5-dioxaphospholane 2-oxide
SMILES: C1COP(=O)(O1)Cl
Synonyms: 6609-64-9, 2-Chloro-1,3,2-dioxaphospholane 2-oxide, 2-Chloro-2-oxo-1,3,2-dioxaphospholane, EINECS 229-560-6, DTXSID70216292

Application

2-Chloro-1,3,2-dioxaphospholane 2-oxide is primarily used as a key intermediate in the synthesis of flame-retardant additives for polymers and textiles. It also serves as a building block for modified oligonucleotides in nucleic acid research, enabling phosphate backbone modifications. In medicinal chemistry, this compound is employed to prepare prodrugs or phosphonate-based therapeutics targeting metabolic pathways.

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